effect of anti phospholipid antibodies on in vitro fertilization/intracytoplsmic sperm injection outcome

نویسندگان

elham azimi nekoo school of medicine, medical sciences/university of tehran, tehran, iran

ensieh shahrokh tehrani nejad reproductive health research center, medical sciences/university of tehran. department of endocrinology, royan institute

batool rashidi reproductive health research center, medical sciences/university of tehran

hossein kilani department of endocrinology, royan institute

چکیده

objective: the study aimed to determine the relationship between presence of antiphospholipid antibodies (apls) and clinical pregnancy rate in patients undergoing ivf/icsi procedures. materials and methods: this descriptive-analytic study performed on two hundred consecutive women referred for ivf/icsi in vali-e-asr reproductive health research center. serum levels of apls , anticardiolipin [acl], antiphosphatidic acid [apa], antiphosphatidyl choline [apc] and antiphosphatidylserine [aps] were checked for all patients before starting ivf cycles. apls  seropositivity and clinical pregnancy rate were determined. t-test and mann-whitney were used to compare two groups. p value <0.05 was considered significant. results: 23 women (11.5%) were apl positive. twenty nine women of 177 apl seronegative patients (16.4%) became pregnant while only one of 23 seropositive patients (4.3%) was pregnant. clinical pregnancy rate was not significantly different in two groups. conclusion: although apls were common, these antibodies did not affect the outcome of ivf/icsi procedures. thus screening for apls is not recommended in women undergoing these procedures.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation

in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.

Predicting Implantation Outcome of In Vitro Fertilization and Intracytoplasmic Sperm Injection Using Data Mining Techniques

Objective The main purpose of this article is to choose the best predictive model for IVF/ICSI classification and to calculate the probability of IVF/ICSI success for each couple using Artificial intelligence. Also, we aimed to find the most effective factors for prediction of ART success in infertile couples. MaterialsAndMethods In this cross-sectional study, the data of 486 patients are colle...

متن کامل

: the effect of sericin levels (silk glue protein) on rate of in vitro maturation, fertilization and culture of sheep oocytes

هدف از آزمایش اول بررسی اثر سطوح مختلف سریسین [0 (control), 0.1, 0.5, 1.0, 2.5 %] افزوده شده به محیط , ivm بر cumulus cell expansion، بلوغ هسته و توسعه متوالی جنین، در گوسفندان نژاد سنجابی در فصل تولید مثلی می باشد. از سرگیری میوز به وسیله خارج شدن اولین پولار بادی اندازه گیری و هم چنین درصد رسیدن جنین های دو سلولی به مرحله کلیواژ و بلاستوسیت نیز به عنوان نشانه ای از میزان شایستگی توسعه اولیه ج...

Anti-phospholipid/Cofactor Antibodies

Following a meeting at Sapporo, Japan, an international consensus statement on preliminary classification criteria for definite anti-phospholipid syndrome was published.1 This set of criteria is divided into the clinical part which includes vascular thrombosis and pregnancy morbidity and the laboratory part which includes anti-cardiolipin (aCL) antibody and lupus anti-coagulant tests. Diagnosis...

متن کامل

O-32: Effects of Intrauterine Injection of Recombinant Human Chorionic Gonadotropin before Embryo Transfer on Outcome of In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Randomized Clinical Trial

Background: To evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhCG) before embryo transfer (ET). Materials and Methods: In this randomized placebocontrolled clinical trial, a total number of 182 infertile patients undergoing their first in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) were randomly assigned to receive 250 μg i...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of family and reproductive health

جلد ۱، شماره ۱، صفحات ۳۶-۴۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023